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KMID : 0882420100790050549
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Korean Journal of Medicine
2010 Volume.79 No. 5 p.549 ~ p.552
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A case of propofol-induced anaphylaxis
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Chung In-Kwon
Jeon Seong-Woo
Kim Sung-Uk
Sohn Jong-Won
Chung Duk-Won
Jung Min-Kyu
Kim Sung-Kook
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Abstract
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Propofol is widely used for sedation during endoscopy. Hemodynamic compromise and respiratory depression might occur under propofol sedation, whereas anaphylaxis is rare. We recently experienced this rare side effect. A 71-year-old woman suffering from substernal chest discomfort underwent endoscopic examination under propofol sedation. She denied any history of allergic reaction to drugs or foods such as beans and eggs. After completion of the endoscopic examination, she developed a whole-body rash with pruritus and edema of her face, including the eyelids and lips. Hypotension was seen on physical examination, and her oxygen saturation was decreased on pulse oximetry. She recovered completely after treatment with epinephrine, an antihistamine, and steroids, with supportive care. Anaphylaxis to propofol is a rare side effect, and prompt treatment is mandatory when it develops.
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KEYWORD
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Propofol, Anaphylaxis, Conscious sedation
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